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Helping Patients With Parkinson鈥檚 Live a Better Life

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Author(s)

Justin Beach

Jon Stone

Media Relations Manager

Jon Stone

Research at 91桃色 is aimed at reducing the side effects of Parkinson鈥檚 disease

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Deteriorating motor skills, uncontrollable tremors, the inability to perform everyday tasks. Those are the challenges that as many as one million Americans with Parkinson鈥檚 disease face every day. There is no cure for the disease, but medication and therapy is used to treat symptoms.

鈥淭his is going to help patients with Parkinson鈥檚 disease,鈥 says associate professor听听about the work he is doing in his computer engineering lab at the 91桃色. 鈥淲e are processing human brain signals to recognize human activities from core brain signals.鈥

His research started three years ago and continues now, thanks in part to the opening of the听听at 91桃色. The institute focuses on finding ways to increase the healthy years of life by encouraging interdisciplinary coursework and research at 91桃色, and by collaborating with community partners.

Mahoor鈥檚 research centers on helping patients with Parkinson鈥檚 find a better way to live with the side effects of the disease. One method uses deep brain stimulation (DBS) which involves the implantation of a device called a neurostimulator (sometimes called a 鈥渂rain pacemaker鈥), which helps send electrical impulses to specific targets in the brain.

One issue with the current DBS system is that doctors have to make adjustments depending on the types of activities the patient is doing. Mahoor hopes to be able to change that. 鈥淲e are trying to use machine-learning techniques and computer algorithms to recognize a patient鈥檚 behaviors,鈥 he says. 鈥淥nce we recognize behaviors, then we can adjust the DBS parameters and the signals.鈥

This research would not be possible without collaboration. Twelve graduate students and one post-doctoral student are helping with the research at 91桃色. Mahoor has also partnered with the听听(颁狈滨).

鈥淲e record brain activity in surgery from patients who are undergoing deep brain stimulations,鈥 says Sara Hanrahan, a scientist with CNI. 鈥淲e want to use those signals to understand what the patient is doing at any time so we can have a DBS personalized for that patient.鈥

Mahoor says without the data and testing being done by CNI, his work would not be possible. 鈥淒octors and engineers are working together to solve a scientific problem,鈥 he says. 鈥淚t鈥檚 not something I can do by myself as an engineer by sitting in my office and coming up with an algorithm. That鈥檚 the kind of collaboration that we are doing.鈥

Doctors and engineers are working together to solve a scientific problem. It鈥檚 not something I can do by myself as an engineer by sitting in my office and coming up with an algorithm. Mohammad Mahoor, Dept. of Electrical & Computer Engineering